Aging and Women’s Health

Researchers in this cluster examine the health effects of aging and associated decline in reproductive hormones in women. Outcomes of interest include mental health, cognitive functioning, cardiovascular health, and menopausal symptoms (e.g. hot flashes, sleep disturbance). Hormonal and behavioural interventions aimed at preventing age-related declines in women’s health are also a focus of recent investigations.

Jennifer Gordon, Ph.D., Canada Research Chair in Women’s Mental Health, and Assistant Professor, Psychology, University of Regina.

Cluster Members

Gordon JL, Rubinow DR, Watkins L, Hinderliter AL, Caughey MC, Girdler SS. (in press). The effect of transdermal estradiol and micronized progesterone on markers of risk for arterial disease in peri- and early postmenopausal women. Journal of Clinical Endocrinology and Metabolism

Gordon, JL, Rubinow, DR, Eisenlohr-Moul, TA, Xia, K, Schmidt, PJ, Girdler, SS. (2018). Efficacy of transdermal estradiol and micronized progesterone in the prevention of depressive symptoms in the menopause transition: a randomized clinical trial. JAMA Psychiatry). 75(2), 149-157.

Gordon JL, Girdler SS, Meltzer-Brody S, Stika CS, Thurston RC, Clark CT, Prairie BA, Moses-Kolko E, Joffe H, Wisner KL. (2015). Ovarian hormone fluctuation, neurosteroids and HPA axis dysregulation in perimenopausal depression: a novel heuristic model. American Journal of Psychiatry. 172(3), 227-236.

Gordon JL, Rubinow DR, Eisenlohr-Moul TA, Leserman J, Girdler SS. (2016). Estradiol variability, stressful life events and the emergence of depressive symptomatology during the menopause transition. Menopause. 23(3), 257-266.

Gordon JL, Rubinow DR, Thurston RC, Paulson J, Schmidt PJ, Girdler SS. (2016). Cardiovascular, hemodynamic, neuroendocrine, and inflammatory markers in women with and without vasomotor symptoms Menopause. 23(11), 1189-1198.

For more information, contact cluster leader Dr. Jennifer Gordon at jennifer.gordon@uregina.ca